Benign and Malignant Tumors And Tumor-Like Conditions of Fibrous Tissue

Frequency of Cytomegalovirus (CMV) in benign and malignant tumors

Cytomegalovirus (CMV) is a widespread pathogen that is found in milk, saliva, urine, cervical secretions, and semen fluid. It is supposed that CMV is a risk factor for breast cancer. The aim of this study was to determine the frequency of CMV among benign and malignant breast tumors. Paraffin embedded breast carcinoma (n=24) and fibroadenoma (n=24) samples were collected from Toos and Firoozgar...

Absence of Human Papillomavirus in Benign and Malignant Breast Tissue

Background & Objective: Malignant breast tumors, which are one of the most important deadly cancers in women, like many other cancers, are proposed to be related to viruses etiologically. Proper management of breast carcinoma necessitates an identification of the etiological factors. Human Papillomavirus is considered to have an etiological role in breast carcinoma. We...

MTA1 Expression in Benign and Malignant Salivary gland Tumors

Introduction: Salivary gland tumors (SGTs) are important parts of human neoplasms. The most common SGT is pleomorphic adenoma and the most common malignant SGTs are mucoepidermoid carcinoma and adenoid cystic carcinoma (ACC). Metastasis-associated genes 1 (MTA1), a member of the nucleosome remodeling and histone deacetylation complex, is one newly discovered gene which recruits histone deacetyl...

Neoangiogenesis in Benign and Malignant Salivary Gland Tumors

Introduction: There are few studies investigating the role of neoangiogenesis in biological behavior of salivary gland tumors. CD105 expression has demonstrated greater accuracy for detecting new vessel formation compared with other pan-endothelial molecules. This study aimed to assess and compare intratumoral Micro-Vessel Density (MVD) through using immunohistochemichal expression of CD105 bio...

Molecular markers in benign and malignant soft tissue tumors